Pharmacologically Active Carnitine Analog Formula

 

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This is an open-minded formula…

New QUADRACARN™ from Beverly International Nutrition is the world's first formula containing 4 scientifically studied carnitine analogs plus Gymnema sylvestre leaf extract, all tested and reviewed for purity and carefully balanced for maximum pharmacokinetic and pharmacodynamic impact. Unlike so many of today's narrow-minded "specialist" formulas, QUADRACARN™ is a "generalist" that offers extremely multi-faceted, pharmacologically active functionality.


…capable of at least 21 interconnected pharmacological actions…

"Specialist" supplements focus on only one or a few actions, such as stimulating protein synthesis or nitric oxide (NO). However, building a better looking body -the #1 goal cited by supplement consumers- involves a long list of interconnected actions across many dimensions -tissue, cellular, genetic, nutritional, metabolic, and so on-all of them interconnected.


…with the potential to affect how you lift a barbell to how you perform in the bedroom.

Scientific studies have revealed that the very same carnitine analogs found in QUADRACARN™ are capable of producing a total of at least 21 interconnected pharmacological actions that affect the way your body looks and performs (both in the gym and the bedroom), nerve and mitochondrial health, blood flow, NO, how quickly you age, insulin and testosterone effectiveness, cholesterol, hair loss, and much more. QUADRACARN™ is a year-round, life-long formula for anyone who truly cares how they look and perform today, and how they'll look and perform for the remainder of their life.


Potential Benefits of QUADRACARN™ Supplementation:

Androgen Receptor (AR) levels Muscle Mass
Androgen Effectiveness Fat Mass (Body Fat)
Insulin Effectiveness Total Cholesterol
Muscle Fatigue Muscle Damage
Muscle Soreness Nitric Oxide
Blood Flow Oxygen Delivery
Resynthesis of ATP Free Radicals
Mitochondrial Dysfunction Nerve Pain
Nerve Regeneration Hair Growth
Exercise Performance Recovery from Exercise
Erectile Performance  


Six Scientific Bases of QUADRACARN™

1. Carnitine is derived from the amino acids lysine and methionine. Originally thought to be involved only in the conversion of fatty acids into energy, scientists now realize that different types, or analogs, of carnitine offer benefits that go far beyond its role in energy metabolism. [NOTE: Here, "carnitine" is a collective term referring to all analogs of carnitine.]

2. The human body naturally makes, or synthesizes, a small amount of carnitine, principally l-carnitine, n-acetyl-l-carnitine and propionyl-l-carnitine. Though it appears to be capable of synthesizing considerably larger amounts of these analogs, certain factors -scientists are still trying to identify what they are-act to limit this process.

3. Over the past several years a number of studies published in respected, peer-reviewed scientific journals have investigated l-carnitine, n-acetyl-l-carnitine, propionyl-l-carnitine and l-carnitine l-tartrate. The results of these studies indicate that each one of these four carnitine analogs produces a variety of pharmacological actions of interest to anyone who cares about the way they look and perform today, and how they will look and perform for the remainder of their life.

4. The fact that your body naturally synthesizes carnitine analogs means that they serve some essential roles. This observation alone serves as solid scientific basis on which to build a carnitine analog supplement. However, your body does not synthesize any of above-mentioned analogs in the amounts proven to be of value in scientific studies. (This is one of the reasons why we refer to the actions reported in these same studies as "pharmacological" in nature.)

5. Each carnitine analog has its own unique chemical structure. Your body will therefore absorb, distribute, metabolize and respond to it differently. In pharmacological terms, we say that each analog has its own unique "pharmacokinetic" and "pharmacodynamic" properties. Thus, by combining several analogs into one formula, you can enjoy a broader range of potential benefits.

6. QUADRACARN™ contains a fusion of all 4 of the carnitine analogs studied to date (i.e. l-carnitine, n-acetyl-l-carnitine, propionyl-l-carnitine and l-carnitine l-tartrate). They are included in amounts that, when the product is used as directed, are capable of producing the pharmacological actions reported in scientific studies. Beverly's R&D scientists also added an extract of Gymnema sylvestre leaf extract for its potential to increase insulin effectiveness and, thereby, your ability to respond to carnitine. Finally, all ingredients have been tested and reviewed for purity and painstakingly balanced with respect to one another for maximum pharmacokinetic and pharmacodynamic impact. These features combine to make QUADRACARN™ distinct from any other product on the market.

 

Achieve greater "Androgen Effectiveness"…

Androgens are hormones involved in sex drive, muscle growth, cardiovascular health, mood and more. The best known androgen is testosterone. How effectively your androgens work -your "Androgen Effectiveness"--depends to a large degree on the number of androgen receptors (ARs) present inside and on the surface of your cells. Whether you're a man or a woman, having greater androgen effectiveness allows you to gain more muscle size and strength from training, and it can also affect your sexual performance, blood lipid levels, your risk of heart disease and osteoporosis, and even how happy or depressed you feel.

A study published in the well-respected journal Medicine & Science in Sports & Exercise found that dietary supplementation with one of the four analogs found in QUADRACARN™ can actually increase AR levels in resistance training subjects and that this may enhance recovery from their workouts. Considering the many roles played by androgens in human physiology -sex, muscle, mood and more-- the boost in androgen effectiveness may provide you with many more benefits than just faster recovery.

…and more "Bedroom Power"

One of the ways in which carnitine may increase blood flow and oxygen delivery is by enhancing NO signaling. NO is a tiny molecule that serves as a carrier of signals, or messages, between cells. The active ingredient in Viagra® is sildenafil, which enhances NO signaling by inhibiting the breakdown of a signaling molecule known as cyclic GMP.

A study published in Current Medical Research & Opinion found that patients with erectile dysfunction who received the combination of sildenafil and a carnitine analog found in QUADRACARN™ experienced significantly better erections and "successful intercourse attempts" (their words) than did subjects who received only sildenafil.

SCIENTIFIC EVIDENCE

Broad et al. (2008). Int J Sport Nutr Exer Metab, 18: 567.
Cao et al. (2009). Clin Invest Med, 32(1): E13.
Chiechio et al. (2007). CNS Drugs, 21 (Suppl 1): 31.
Foitzik et al. (2007). Exp Dermatol, 16(11): 936.
Kraemer et al. (2006). Med Sci Sports Exer, 38(7); 1288.
Malaguarnera et al. (2007). Am J Clin Nutr, 86(6): 1738.
Rebouche CJ (2004). Ann NY Acad Sci, 1033: 30.
Spiering et al. (2008). J Strength Cond Res, 22(4): 1130.
Volek et al. (2002). Am J Physiol Endocrinol Metab, 282: E474.



$34.95
(120 tablets)

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Sorry! We are unable to ship internationally at this time.

 


QUADRACARN™ Frequently Asked Questions (FAQ)


1. What is QUADRACARN™?

QUADRACARN™ is a dietary supplement containing 4 scientifically studied analogs of carnitine (l-carnitine, n-acetyl-l-carnitine, propionyl-l-carnitine and l-carnitine l-tartrate) plus Gymnema sylvestre leaf extract. Carnitine is a substance produced naturally by the human body in small quantities. Once thought to be involved only in the conversion of fat into energy, scientists have since learned that it has many far-reaching actions critically related to your appearance, performance and overall health and longevity. These benefits have been documented in studies using the same carnitine analogs found in QUADRACARN™.


2. Can anyone use QUADRACARN™?

QUADRACARN™ is intended for several times daily use as a dietary supplement by men and women 18 years of age and older who wish to improve their appearance, performance and overall health and longevity.


3. What makes QUADRACARN™ different from other physique and performance supplements?

a. 21 Pharmacological Actions: QUADRACARN™'s ingredients were carefully selected on the basis of their ability to produce at least 21 different interconnected pharmacological actions (listed below) of far-reaching and critical importance to your appearance, performance, and overall health and longevity. The human body does not synthesize any carnitine analogs in the amounts shown to produce these actions in scientific studies; hence the term "pharmacological actions". However, by supplementing your diet with QUADRACARN™ several times daily you can safely and effectively ingest the amounts of carnitine analogs required to produce the pharmacological actions reported in the aforementioned studies.

b. Tested for Safety & Purity: All of the ingredients in QUADRACARN™ have been tested and reviewed for safety and purity. This is standard protocol in the development of each new Beverly supplement.

c. Pharmacokinetically & Pharmacodynamically Balanced: "Pharmacokinetics" refers to what your body does to an ingested substance, including how it is absorbed and excreted. "Pharmacodynamics" refers to what the substance does to your body, including any beneficial outcomes. Because each carnitine analog has a different chemical structure, it has its own unique pharmacokinetic and pharmacokinetic properties. Thus, by combining several analogs in one formula, you can enjoy a greater range of potential benefits. QUADRACARN™ contains a proprietary combination, or fusion, of 4 scientifically studied carnitine analogs. Each analog has been balanced both with respect to the others and the Gymnema extract for maximum pharmacokinetic and pharmacodynamic impact.

d. Clinically Proven to Work: All of the carnitine analogs found in QUADRACARN™ have been proven to provide a variety of benefits in clinical studies involving humans. As indicated above, QUADRACARN™ contains sufficient amounts of each carnitine analog to allow you to duplicate the results of these studies safely and effectively.

e. Looks and Longevity: Many of the pharmacological actions reported for carnitine analogs in scientific studies can affect not only the way you look and perform, but also how quickly you age. For instance, one of the carnitine analogs found in QUADRACARN™ displays properties which can reduce mitochondrial dysfunction (blamed as a major cause of aging) and even promote the regeneration of nerves. In addition, carnitine analogs can have beneficial effects on your cholesterol level, androgen (e.g. testosterone) and insulin effectiveness, muscle mass, fat mass, fatigue, soreness, cardiovascular health and more. In short, QUADRACARN™ isn't just for those of us who want to look and perform great today. It is a multi-faceted formula for anyone who cares about how they look and perform for the rest of their life.

f. Flexible: QUADRACARN™ can be stacked with any other Beverly product to take advantage of synergy and otherwise encourage even greater results.

g. Entirely Stimulant-Free: QUADRACARN™ is entirely free of caffeine and other stimulants. It therefore does not produce the undesirable side effects associated with these substances and is easily tolerated no matter what time of day it is taken. Indeed, for the best results QUADACARN™ should be taken several times daily as a synergistic supplement to your diet and training.


4. When can I expect to see results while using QUADRACARN?

Studies suggest that it can take anywhere from 3-6 hours for the level of carnitine in your circulation to reach a maximum when taking carnitine supplements. (Here, "carnitine" refers to all analogs of carnitine.) Depending on the dosage, it may take up to 3 days or more before your carnitine level achieves what scientists refer to as a "steady state". That being said, it is quite possible for QUADRACARN™ uses to experience noticeable improvements in their physique (e.g. vascularity, muscle volumization or fullness) and performance (e.g. mood, energy and cognitive function) within 1-2 weeks of using it several times daily. Scientific studies suggest that supplementation with carnitine analogs can continue to provide beneficial pharmacological actions for months, or essentially, as long as you continue to take them.


5. Can I stack QUADRACARN™ with UP-LIFT™?

Yes. As noted above, QUADRACARN™ can be combined with any other Beverly product. For instance, users have reported even harder and longer-lasting pumps when stacking QUADRACARN™ with UP-LIFT™. This may be explained by a powerful synergy between the ingredients found in each product.


6. If I don't perform resistance exercise, can I still benefit from using QUADRACARN™?

QUADRACARN™ is capable of providing you with benefits whether or not you exercise. However, you can expect far greater benefits when using QUADRACARN™ as a supplement to a calorically-appropriate diet and a regular program of cardiovascular and resistance exercise. Because resistance exercise is more efficient at stimulating muscle protein synthesis, you can expect greater gains in muscle mass, strength, shape, tone and definition when using QUADRACARN™ while performing this type of exercise.


7. What are the benefits of using QUADRACARN™ over the long term?

QUADRACARN™ contains ingredients that clinical, animal and experimental studies suggest can encourage*:

Androgen Receptor (AR) levels Muscle Mass
Androgen Effectiveness Fat Mass (Body Fat)
Insulin Effectiveness Total Cholesterol
Muscle Fatigue Muscle Damage
Muscle Soreness Nitric Oxide
Blood Flow Oxygen Delivery
Resynthesis of ATP Free Radicals
Mitochondrial Dysfunction Nerve Pain
Nerve Regeneration Hair Growth
Exercise Performance Recovery from Exercise
Erectile Performance  


8. Is QUADRACARN™ safe for people with medical conditions?

In scientific studies, carnitine supplements have been given to 100-year-old subjects and subjects with medical conditions. These studies have reported a variety of positive results from carnitine supplementation. Also note that QUADRACARN™ was tested on healthy exercising individuals during the product development stages. Nevertheless, it is advised that you discuss QUADRACARN™ with your medical doctor before using if you have a medical condition, or if you are currently unaware of your health status.


9. Is QUADRACARN™ safe if you are trying to become pregnant, or are currently pregnant or nursing?

Discuss QUADRACARN™ with your medical doctor before using if you are trying to become pregnant, or are currently pregnant or nursing.


10. Can QUADRACARN™ be used during preparation for a bodybuilding competition? What about a fitness or figure competition?

Yes. Physique competitors of all kinds need to hold onto as much of their muscle mass as possible while burning fat. During the product development stages Beverly tested QUADRACARN™ on subjects who were dieting for physique competitions. They found that rather than merely holding onto more muscle mass while dieting, the subjects actually gained muscle and experienced improvements in shape, tone, vascularity and definition. This is unusual in that the calorie-restricted diets followed by physique competitors typically result in muscle wasting (atrophy). These benefits were only observed when the subjects took relatively large doses of carnitine analogs. These doses can easily be achieved when QUADRACARN™ is used as directed.


11. Can I stack other Beverly products with QUADRACARN™?

Yes. QUADRACARN™ was designed to be complementary to every other Beverly product. Contact our customer service team for help in developing your ideal physique and performance stack. Contact information is provided below.


12. I just want to look slim and toned. I don't want to gain muscle. Is QUADRACARN™ suitable for me?

Yes. The quantity, or mass, of muscle on your body plays a critical role in determining its shape, tone, curves and lines. Thus, it is important that you take steps to protect your muscle mass while reducing fat mass, particularly if you aren't performing resistance exercise on a regular basis. Ingredients found in QUADRACARN™ have been shown to produce pharmacological actions of importance to both maintaining muscle mass and reducing fat mass.


13. I want something to help me avoid aging, or at least slow it down a bit. What kind of benefits can QUADRACARN™ provide me with?

All of the 21 pharmacological actions listed above (answer to question 7) have the potential to delay or even reverse certain facets of aging. For instance, with age your neurons (nerve cells) tend to accumulate damage. This can increase your risk of neurological diseases like dementia and Alzheimer's. Studies on n-acetyl-l-carnitine, a carnitine analog found in QUADRACARN™, indicate that it can protect neurons from damage, including cell death, termed apoptosis.

Another example comes from the mitochondria, which are the "power plants" of your body's cells. They supply almost all of the cells' energy needs. Like neurons, mitochondria tend to break down over time. This has been blamed as a major cause of aging. Experimental studies suggest that n-acetyl-l-carnitine can protect mitochondria from damage. In animal studies, n-acetyl-l-carnitine has been found to actually increase mitochondrial mass (i.e. their numbers and/or size) in muscle tissue subject to unloading (disuse). Both actions have the potential to delay or reverse aging.

It's not unusual to experience hair loss as you age. Here QUADRACARN™ may also be of help. A study published in the journal Experimental Dermatology found that l-carnitine l-tartrate (one of the analogs found in QUADRACARN™) extended the period of maximum hair growth when cultured hair follicles were treated with it. This carnitine analog also stimulated the hair follicles to increase in length and reduced the number of them undergoing apoptosis.

Of course, we all know how hard it is to hold onto muscle mass as we age. In a study published in the American Journal of Clinical Nutrition, 100-year-old subjects received l-carnitine (one of the analogs found in QUADRACARN™) or a placebo for 6 months. The subjects who received l-carnitine experienced a reduction in total cholesterol, an increase in muscle mass (by over 8 lbs), a reduction in fat mass (a loss of nearly 4 lbs), a decrease in muscle fatigue, improvements in walking capacity, and an increase in cognitive performance.


14. Where is QUADRACARN™ made?

QUADRACARN™ was formulated and tested by R&D scientists at the Beverly International Nutrition head office in Cold Spring, Kentucky. Each ingredient has been selected based on the results of Beverly's own tests and studies published in publicly-accessible databases such as those made available by the National Center for Biotechnology Information (NCBI).


15. Where can I obtain product support?

Beverly customers receive ongoing support in the form of our own in-house customer service team who has extensive experience working with amateur and professional bodybuilders, models, figure and fitness competitors, powerlifters and other types of athletes with goals similar to yours. Contact information for our customer service team is provided below:

Toll-free telephone: 1-800-781-3475
Fax: 859-781-7590
E-mail: bevnut@beverlyinternational.net
www.beverlyinternational.com

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.



$34.95
(120 tablets)

US Orders Only Please
Sorry! We are unable to ship internationally at this time.

 


One Month with Quadracarn™
By Kevin Rodriguez

Editor's Note: A pseudonym has been used in this article in place of the actual name of the product tester.


How much better?

When I was asked to test Beverly's latest product, I was mildly enthused. The name sounded intriguing --"Quadracarn" makes me think of a souped-up four-wheel drive car-but the main ingredient, carnitine, isn't exactly headline news. This was my opinion one month ago, anyways.

Granted, I had never used a supplement containing four different analogs of carnitine (more about this later), and certainly not in the precise ratios found in Quadracarn™. (It also contains Gymnema sylvestre leaf extract.). And, yes, Beverly is known for having the highest quality formulas in the world. If you see an ingredient listed on the label of one of their products, then you know that it is (1) present in precisely the amount specified and (2) of the highest quality available.

Still, how remarkably better could Beverly's formula be from the carnitine supplements of the past? This is the question I asked myself before testing Quadracarn™ for four weeks as a supplement to my diet and training. You'll get the answer in the discussion that follows.


Studying Up

While I waited to receive my shipment of Quadracarn™ from Beverly's R&D laboratory, I decided to get up to date on the science behind this product. Having been schooled in biochemistry, I know how to read a scientific study. A search on PubMed using "carnitine" pulled up over 10,000 results, which I narrowed down by adding keywords like "muscle", "exercise", "supplement", "aging", "nitric oxide" and "testosterone", among others. When I found a study I wanted, I requested a copy from the author, usually a university research scientist who happily obliged.

As the studies arrived in my inbox I devoured them. The more I learned about carnitine's pharmacological powers, the wider my eyes opened, and the more excited I became about testing Quadracarn™. A small sample will show you why…


Androgen Effectiveness

Androgens are hormones involved in sex drive, muscle growth, cardiovascular health, mood and more. The best known androgen is testosterone. How effectively your androgens work depends to a large degree on the number of androgen receptors (ARs) present inside and on the surface of your cells. To transmit a signal, an androgen molecule generally has to bind to an AR. This sets in motion a cascade of biochemical events that can lead to things like muscle protein synthesis, vasodilation, changes in mood, and other good stuff.

The more ARs you have, the more testosterone and other androgen molecules circulating through your body that your cells can respond to. In other words, your "androgen effectiveness" increases. Whether you're a man or a woman, this allows you to gain more muscle size and strength from resistance training, and it can also affect your sexual performance, blood lipid levels, your risk of heart disease and osteoporosis, and even how happy or depressed you feel. The list of potential benefits goes on and on.

In light of the importance of ARs to androgen effectiveness, it was exciting to learn that a clinical study published in the well-respected journal Medicine & Science in Sports & Exercise reported that dietary supplementation with a carnitine analog known as l-carnitine l-tartrate, one of the four analogs found in Quadracarn™, can actually increase AR levels in resistance training subjects and that this may enhance recovery from their workouts. Considering the many roles played by androgens in human physiology -sex, muscle, mood and more-- the boost in androgen effectiveness associated with l-carnitine l-tartrate supplementation may provide more benefits than just faster recovery. I hoped to experience these benefits first hand.


Muscle Protection

Speaking of resistance training, when you lift heavy weights your muscles have to generate lots of force. Doing so physically stresses them, not to mention the metabolic stress caused by the intracellular accumulation of things like free radicals, hydrogen ions, calcium ions, water and so on. Here, too, Quadracarn™ can be of help. A study in the American Journal of Physiology suggests how. The researchers gave experienced resistance training subjects either a placebo or l-carnitine l-tartrate for three weeks. Two days later they performed 5 sets of 15-20 reps of squats.

The subjects who took the carnitine supplement had higher circulating carnitine levels throughout the study, and there was evidence that supplementation reduced free radical generation, muscle tissue damage and muscle soreness, and promoted ATP resynthesis. If this doesn't sound like enough, the authors of the study suggested that carnitine supplementation also may have promoted blood flow during and after the squat workout. They remarked:

"A major assumption of our working hypothesis was that [l-carnitine l-tartrate] supplementation would lead to an accumulation of carnitine in endothelial cells (or prevent carnitine deficiency) and thereby increase blood flow, oxygen delivery, and regeneration of ATP. In general, the results support our hypothesis…."


Nitric Oxide

One of the ways in which carnitine may increase blood flow and oxygen delivery is by enhancing NO signaling. NO is a tiny molecule that serves as a carrier of signals, or messages, between cells. Besides its role in vasodilation (relaxing blood vessels, thereby encouraging faster flow of blood), NO also regulates oxygen consumption and ATP production within mitochondria (discussed below), protecting them from damage under low oxygen (hypoxic) conditions such as may occur during high intensity exercise. This agrees with another study involving resistance training subjects which was published in the Journal of Strength and Conditioning Research in 2008. The addition of l-carnitine l-tartrate to the subjects' diets appeared to protect their muscles from hypoxic stress.


Nerve Protection

Your muscles would be pretty silent without your nerves. The nervous system tells them when to "jump" (contract) and "how high" (how much force to generate). This isn't the only reason you need to treat your nerves well. The older you get, the more wear and tear nerve cells (neurons) suffer and the greater tends to be your risk of neurological diseases like dementia and Alzheimer's. Studies on n-acetyl-l-carnitine, another carnitine analog found in Quadracarn™, indicate that it can actually protect neurons from damage, including cell death, termed apoptosis.

When you see n-acetyl-l-carnitine talked about in a scientific journal with a title like CNS Drugs, you know it's a serious supplement. In a 2007 review article the authors referred to its ability to prevent and treat nerve pain. They added that "[n-acetyl-l-carnitine] can also improve the function of peripheral nerves by increasing nerve conduction velocity, reducing sensory neuronal loss, and promoting nerve regeneration. Recent evidence indicates that [n-acetyl-l-carnitine] regulates processes that go beyond its classical role in energy metabolism."


Mitochondria Protection

Neurons, muscle cells and most other cells in your body depend on mitochondria for energy. In total, these cigar-shaped structures produce more than 95% of your energy needs. Producing this much energy is a huge responsibility for the tiny mitochondria. Not surprisingly, they tend to break down over time. Termed "mitochondrial dysfunction", this has been blamed as a cause of aging.

At the least, it can result in reduced ATP production and increased free radical generation with damaging effects. Experimental studies suggest that n-acetyl-l-carnitine may slow and possibly even reverse aging by protecting mitochondria from losing function. In animal studies, n-acetyl-l-carnitine has been found to increase mitochondrial mass in muscle tissue subject to unloading (disuse). Bodybuilders usually focus on building muscle mass, but if you're interested in getting huge and living a long, high performance life, don't neglect to build mitochondrial mass.

Hair Protection

Carnitine has roles low and high in the human body. Take your scalp, for instance. A study published in the journal Experimental Dermatology found that l-carnitine l-tartrate extended the period of maximum hair growth when cultured hair follicles were treated with it. This carnitine analog also stimulated the hair follicles to increase in length and reduced the number of them undergoing apoptosis.


Age Reversal (It's never too late!)

I'm getting awfully close to 40. While I'm by no means in my "golden years", it's nice to know that it's never too late to build muscle, lose fat and improve my performance…and that carnitine can help. This is what I learned while reading a study published in the American Journal of Clinical Nutrition. The authors gave 100-year-old subjects l-carnitine (the remaining carnitine analog found Quadracarn™) or a placebo for 6 months. The subjects who received l-carnitine experienced a reduction in total cholesterol, an increase in muscle mass (by over 8 lbs), a reduction in fat mass (a loss of nearly 4 lbs), a decrease in muscle fatigue, improvements in walking capacity, and an increase in cognitive performance. Not bad, huh?


What makes Quadracarn™ so different?

By now you are likely starting to see why I couldn't wait to get my hands on Quadracarn™. Clearly there is a mountain of potential benefits to be had by supplementing your diet and training with carnitine. This, the scientific research convinced me of. But there's even more to Beverly's new breakthrough formula than I've told you…

The human body naturally produces roughly 1.9 mg of carnitine per kilogram of bodyweight per day. Here "carnitine" refers to all forms, or analogs, of carnitine. Several groups of researchers have studied the pharmacodynamic and pharmacokinetic properties of carnitine; essentially, how your body absorbs various carnitine analogs (whether supplied by the diet or dietary supplements) and what it does to them after they have been absorbed. Below are just a few of the observations they've made:

  • A portion of the l-carnitine produced by your body is continually converted into n-acetyl-carnitine and propionyl-l-carnitine.
  • L-carnitine tends to have a longer half-life in the body than n-acetyl-l-carnitine or propionyl-l-carnitine.
  • When you ingest n-acetyl-carnitine, a portion of it is absorbed intact into the circulation.


Pharmacokinetics and Pharmacodynamics make the difference

If your body is continually converting some of the l-carnitine that it makes into n-acetyl-l-carnitine and propionyl-l-carnitine, then it stands to reason that there must be some purpose for these other analogs. Otherwise, it wouldn't make them. This argument rests on solid biochemical as well as pharmacodynamic and pharmacokinetic principles.

Each carnitine analog has a different chemical structure. For instance, l-carnitine lacks the acetyl group found on n-acetyl-carnitine. Your body will therefore respond to each analog differently, which means you can experience different benefits from it. Think about it this way. Every "key" (carnitine analog) fits into a different "lock" (metabolic pathway) and opens a different "door" (produces a different physiological benefit). Sure, there will be some overlap; however, there will also be differences. Thus, by combining several "pre-converted" carnitine analogs into a single supplement formula you can enjoy a broader range of potential benefits. This is what Beverly has done in creating Quadracarn™.

Quadracarn™ contains a proprietary combination, or fusion, of four analogs of carnitine (l-carnitine, n-acetyl-l-carnitine, propionyl-l-carnitine and l-carnitine l-tartrate) plus an extract of Gymnema sylvestre leaf. Gymnema has been added to promote insulin effectiveness, another hormone with powerful roles affecting your physique and performance at any age, including your body's ability to respond to carnitine. All of the carnitine analogs in the formula have been carefully balanced both with respect to one another and the extract of Gymnema for maximum impact.


The First Week with Quadracarn™

A few days after I concluded my research on carnitine, I received a package from UPS. I grabbed my Swiss army knife out of the kitchen drawer, sliced through the packing tape, opened up the shipping box and pulled out a Quadracarn™ bottle full of tablets. The following morning I unscrewed the cap and took my first serving -3 tablets-- with a glass of water right after eating breakfast.

Throughout my one-month test period I took Quadracarn™ with meals. Here is how my dosage schedule looked:

  • Breakfast: 3 tablets
  • Post-training meal (usually dinner): 3 tablets
  • Late evening protein shake (Ultimate Muscle Protein™): 3 tablets

I should point out that the only change to my diet during the test period was the addition of Quadracarn™. I was already taking Up-Lift™ before and during my workouts and drinking 1-2 protein shakes each day made with Ultimate Muscle Protein™. Also, I did not experience any side effects such as stomach discomfort or diarrhea while using Quadracarn™. I found the tablets easy to swallow with water.

Studies suggest that it can take anywhere from 3-6 hours for the level of carnitine in your circulation to reach a maximum when taking carnitine supplements. Depending on the dosage, it may take up to 3 days or more before your carnitine level achieves what scientists refer to as a "steady state".

For these and other reasons I wasn't expecting to experience anything out of the ordinary for a few days. So I was a little caught by surprise when, on the Friday of the first week, I noticed that my muscles and veins were popping out of my skin roughly thirty to forty percent more than usual. It also appeared as if I'd dropped some subcutaneous water, particularly around my abs and calves. The same day I also had better pumps during my chest and arms workout. I could literally feel the blood pulse through my pecs and biceps. I typically mix up 2 scoops of Up-Lift™ with water and sip on it immediately before and during my workout. Adding Quadracarn™ to my supplement stack seemed to ignite some kind of synergy with Up-Lift™ that made my pumps even harder and longer lasting.


The Second Week

Early into the second week I noticed that my mood had improved. I attributed this at least in part to the fact that I looked better. My muscles and veins continued to leap out of my skin and my pumps were still improving. Overall, my physique had a harder, more conditioned look to it. Whether these changes were due to an increase in androgen effectiveness, NO signaling, vasodilation, blood flow, or all of the above, I can't be certain. The bottom line is that Quadracarn™ was making me feel a good deal better about myself. This extra confidence carried over into the bedroom, which is a benefit I consider to be priceless!


The Third Week

The third week was when Quadracarn™ began to affect my recovery. Every so often I like to change things up by reducing my rests between sets. Instead of resting, say, 60 seconds, I'll rest only 30 seconds or less. Usually this makes me very sore. The soreness can last a few days or even a week, depending. During the third week was when I performed one of these "fast" workouts for the first time since I began my test of Quadracarn™. My muscles were considerably less sore afterwards, sufficiently so that I decided to train this way the remainder of the week.

Late into the third week it was plainly evident that the increase in muscle fullness and vascularity that coincided with my use of Quadracarn™ was a 24/7 phenomenon, not a flash in the pan. This product was somehow enabling me to experience more volume in my muscles and veins long after I left the gym.


Fourth Week

The fourth week started off rough. I had to travel to the northeast on business and I missed three days -Monday through Wednesday-- from the gym. Aggravating the situation was that I was not able to stick to my typically clean, bodybuilding style diet. But I did manage to bring Quadracarn™ in my carry-on luggage, and I took it religiously throughout the entire trip.

I'm a hard gainer, which means that when I miss workouts and don't eat properly, my muscles atrophy quickly. This time, it didn't happen. Quite the contrary, I came back from the trip looking more buff and chiseled than ever. My girlfriend even noticed, and she sees me practically every day. She remarked on the size of my biceps and checked out my abs as if she'd never seen them before. Inspired by my results and the extra confidence I had in the bedroom, now she was ready to get on Quadracarn™.

Roger Riedinger, owner of Beverly, later told me that during some of their earliest tests they gave Quadracarn™ to bodybuilders who were dieting for competition. The subjects didn't just find that they could maintain more muscle mass while dieting and taking Quadracarn™. They were actually gaining muscle and seeing improvements in tone and vascularity. This didn't happen until they took higher dosages like I was using. Once they upped their intake to these higher levels -Bamm!-it was like their bodies passed across some biochemical threshold where everything fell into place and Quadracarn's carnitine analogs sprang into body building action. These observations agreed well with mine.


Conclusion

Overall, I was very satisfied with Quadracarn™ and would recommend it to others, as I've done already. During my one-month test I gained muscle fullness, hardness and vascularity. My mood improved. I experienced less muscle pain and soreness after my workouts. Quadracarn™ seemed to act synergistically with Up-Lift™ to give me even harder, long lasting pumps and volumizing effects that persisted well beyond my workouts.

Despite my being a hard gainer, while using Quadracarn™, I didn't have to worry about losing muscle mass. My body seemed to be able to hold onto it more tightly. I can only imagine how this will affect my gains over the course of an entire year.

I also felt more confident while using Quadracarn™. Was this due to a change in AR levels or androgen effectiveness? Maybe an increase in NO levels which in turn affected my neurotransmitter levels? I don't know. What I do know is that I'm approaching the age where my testosterone level is more of a concern. To prepare, I'm always on the lookout for natural ways of increasing my endogenous testosterone production or making the testosterone that I have work more effectively. While I can't say for sure if Quadracarn™ increased my AR levels (this would require invasive medical testing) or otherwise boosted my androgen effectiveness, I did enjoy tremendous peace of mind knowing that I was taking a supplement with ingredients shown to be capable of doing these things. Again, this confidence carried over into my workouts, the bedroom and every other facet of my day.

As of the publishing date of this article, I'm still using Quadracarn™. Be patient, take it religiously and you will not be disappointed. Beverly's products are of notoriously high quality and they contain ingredients in quantities that, when used as directed, work. Like BCAAs, a protein or a training formula, Quadracarn™ is one of those supplements that you always want to be taking. The benefits are far reaching, affecting your androgens, muscles, nerves, NO, mitochondria, aging and more.

If you stop eating, you eventually run out of energy and nutrients. Taking a carnitine supplement is similar. If it raises your circulating carnitine level to a new, higher value, then you can't expect that it will remain at this value once you stop taking the supplement. Like eating, in other words, Quadracarn™ needs to become a regular part of your lifestyle if you want to continue reaping the benefits.

By the end of the fourth week I saw absolutely no deterioration of any of the benefits that I received while using Quadracarn™. I continued to get compliments on the look of my muscles, with their heightened fullness, vascularity and definition. My mood was as positive as ever, at least in part because I knew I was taking the very best carnitine analog formula available with which to build my body and keep it performing at its best for many years to come.

Whether or not you've tried carnitine supplements in the past, you really can't compare them with Quadracarn™. Its proprietary fusion of carnitine analogs has been carefully balanced to maximize the array of pharmacokinetic and pharmacodynamic properties and the potential benefits that you will experience from using it. This, in my opinion, is what really makes the difference.



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